Read about our epigenetic microarray technology:

Epigenetic Microarrays

This cover-story in Nucleic Acids Research received extensive world-wide feedback and was one of the most downloaded NAR papers in 2006.



Schumacher lab on the road:
Seminars



Read about our study on epigenetics of late-onset Alzheimer's disease:

Epigenetic patterns in the AD brain



Have a look at our study of epigenetic changes in schizophrenia and bipolar disorder:
Epigenetic variation in major psychosis

This study provides evidence of silencing of genes responsible for communication with the brain, brain development and other processes linked to schizophrenia and bipolar disorder. This report was covered in several news stories around the world.

Science news:
Headlines by Fresh Content.net



Our research in the News
(selection):



Science a GoGo
Biomedicine
CAMH announcement
The Globe and Mail
CBC News
Science news



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P R O T O C O L S

You will find here several protocols, which are used in epigenetic profiling. I tried not only to provide each step of the protocol, but also to add hints, notes, tips and tricks, making it as easy as possible to perform a successfull experiment.

DNA Methylation profiling:

Schumacher's Guide #1: Bisulfite conversion of DNA for methylation finemapping.

View as HTML file      Protocol 1
Download as PDF file (94.5 kb)   Protocol 1

Schumacher's Guide #2: Design and application of microarrays for identifying of DNA methylation.

View as HTML file      Protocol 2
Download as PDF file (970 kb)   Protocol 2


An old sketch.











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